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Biohaven Licenses Oral, Brain-Penetrant for Immune-Mediated Brain Disorders

Anticipates initiating Phase 1 clinical development in 2023.

Biohaven Ltd., acquired global rights, excluding China regions, for the development of an oral, brain-penetrant, dual inhibitor of Tyrosine Kinase 2 (TYK2) and Janus Kinase 1 (JAK1) for the treatment of brain disorders. BHV-8000 (previously TLL-041) was licensed from Hangzhou Highlightll Pharmaceutical Co. Ltd. (Highlightll) and Biohaven anticipates advancing the agent into a Phase 1 study in 2023. There is currently no brain penetrant, selective, dual TYK2/JAK1 inhibitors approved for brain ...

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